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Also known as leukocytes, white blood cells (WBCs) are the cells of the immune system that guard the body against infectious diseases, allergens, and other foreign invaders. The number of white blood cells in the blood can frequently inform your doctor whether a disease is present.

Per microliter of blood, there are normally between 4,000 and 11,000 white blood cells. Therefore, having more WBCs in the blood than normal results in a condition known as leukocytosis while having fewer WBCs than normal is called leucopenia.

Types of White Blood Cells

White blood cells come in various types, each with a very distinct function:

  • Neutrophils: Defends the body against bacteria or fungi
  • Eosinophils: Have an important role in allergic reactions and other roles like autoimmune diseases, and certain diseases of the spleen and central nervous system.
  • Basophils: Produces histamine and heparin, chemical substances that guard the body against allergens and other invaders
  • B cells: Create antibodies that can bind to viruses and aid in their destruction
  • T cells: They often come in three types; helper cells, cytotoxic cells, and natural killer cells. Together, they support immune system integrity and coordination of the immunological response.
  • Monocytes: In addition to performing the same role as neutrophils in fighting infections, monocytes also deliver bits of pathogenic bacteria and other organisms to T cells so that they can be eliminated.

Common White Blood Cell Disorders

There are two primary types of white blood cell disorders namely proliferative and leukopenia.

  • Proliferative disorders are characterized by an increase in the number of white blood cells, which can result from cells being destroyed by an illness or even by other conditions.
  • In leukopenia, there’s a decrease in the number of white blood cells which might be brought on by the sickness or other disorders that cause cells to be killed.
  • Neutropenia is a specific type of leucopenia, characterized by a decrease in the number of neutrophils in the blood. External causes of neutropenia could include chemotherapy, medications, toxins, and viral illness. Defects of the bone marrow are among the disorders within the body that can also cause neutropenia.
  • Both neutropenia and leucopenia can result in immune system deficiencies, which can raise the risk of infection. The underlying causes for the change in cell counts are the focus of treatment for leucopenia and neutropenia.
  • Leukocytosis on the other hand is an increase in the number of white blood cells. This condition can be caused by inflammation and other disorders that result in increased bone marrow production. This leads to greater production of WBCs.
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